May 152012
 
  1. Heavily fractured market and small market shares
  2. Rate and nonlinearity of regulatory change
  3. Irregularity of medical training and prescribing practice
  4. General macroenvironmental unpredictability
  5. TRIPS and its effects on innovation
  6. Unfavourable pricing models, including eg the Anhui model
  7. Relatively limited out-of-pocket market
  8. Unsophisticated salesforce techniques
  9. Geographical factors and multi-speed market
  10. Undeveloped marketing communications